We study how to translate and scale-up evidence-based interventions and policies within clinical and community settings in order to improve population health ...
Mission. The central mission of the CUNY ISPH is to translate research into sustainable, cost effective population level interventions, strategies, initiatives ...
ISPH is a leading international school in Hanoi offering extensive programmes of study for 3 to 18 year olds. Based on the UK curriculum and including the ...
function. Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl ...
The central mission of the CUNY ISPH is to translate research into sustainable, cost effective population level interventions, strategies, initiatives and ...
Structure of active IspH enzyme from Escherichia coli provides mechanistic insights into substrate reduction.
IspH catalyzes the reductive dehydroxylation 4-hydroxy-3-methylbut-2-enyl diphosphate into a 5-6:1 mix of IPP and DMAPP [Rohdich02, Rohdich03, Adam02, Hintz01].
23 dec 2020 · Here we describe a class of IspH inhibitors and refine their potency to nanomolar levels through structure-guided analogue design. ... Proteomic ...
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The methylerythritol phosphate pathway of isoprenoid biosynthesis is an attractive anti-infective drug target. The last two enzymes of this pathway, ...