The M41, known informally and more commonly as the Pamir Highway (Russian: “Pamirsky Trakt”, Памирский тракт) is a road traversing the Pamir Mountains through Afghanistan, Uzbekistan, Tajikistan, and Kyrgyzstan in Central Asia.

The road is the only continuous route through the difficult terrain of the mountains and serves as the main supply route to Tajikistan’s Gorno-Badakhshan Autonomous Region. The route has been in use for millennia, as there are a limited number of viable routes through the high Pamir Mountains. The road formed one link of the ancient Silk Road trade route. M41 is the Soviet road number, but no road number is generally signposted along the road today, only destinations.

In the 1985 film Spies Like Us, the decoy GLG-20s played by Chevy Chase and Dan Ackroyd are told to meet their contacts on the “road to Dushanbe,” a reference to the Pamir Highway.