Differentially regulated signaling pathways employed by M. anisopliae and M. acridum infecting cockroach and locust cuticles.
Both the MAP kinase and cAMP dependent protein kinase A (PKA) pathways were activated by M. anisopliae and M. acridum infecting cockroach and locust cuticles. PLC, phosphatidyl inositol-specific phospholipase C; PIP2, phosphatidylinositol 4,5-bisphosphate; IP3, inositol 1,4,5-triphosphate; DAG, diacylglycerol; PKC, protein kinase C; CaMK, calcium/calmodulin regulated kinase; ERK, extracellular signal-regulated protein kinase; CREB, a basic leucine zipper transcription factor that is a potential cAMP response element-binding protein; CO, conidium; AP, appressorium. Thicker arrows indicate pathways that are more highly expressed by M. acridum on either locust or cockroach cuticles.
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