WO2014107664A1 - Compositions and methods for controlling a honey bee parasitic mite infestation - Google Patents
Compositions and methods for controlling a honey bee parasitic mite infestation Download PDFInfo
- Publication number
- WO2014107664A1 WO2014107664A1 PCT/US2014/010347 US2014010347W WO2014107664A1 WO 2014107664 A1 WO2014107664 A1 WO 2014107664A1 US 2014010347 W US2014010347 W US 2014010347W WO 2014107664 A1 WO2014107664 A1 WO 2014107664A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- hop
- strip
- hive
- corrugated
- acids
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N61/00—Biocides, pest repellants or attractants, or plant growth regulators containing substances of unknown or undetermined composition, e.g. substances characterised only by the mode of action
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K47/00—Beehives
- A01K47/04—Artificial honeycombs
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K51/00—Appliances for treating beehives or parts thereof, e.g. for cleaning or disinfecting
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01M—CATCHING, TRAPPING OR SCARING OF ANIMALS; APPARATUS FOR THE DESTRUCTION OF NOXIOUS ANIMALS OR NOXIOUS PLANTS
- A01M1/00—Stationary means for catching or killing insects
- A01M1/20—Poisoning, narcotising, or burning insects
- A01M1/2005—Poisoning insects using bait stations
- A01M1/2011—Poisoning insects using bait stations for crawling insects
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01M—CATCHING, TRAPPING OR SCARING OF ANIMALS; APPARATUS FOR THE DESTRUCTION OF NOXIOUS ANIMALS OR NOXIOUS PLANTS
- A01M1/00—Stationary means for catching or killing insects
- A01M1/20—Poisoning, narcotising, or burning insects
- A01M1/2022—Poisoning or narcotising insects by vaporising an insecticide
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01M—CATCHING, TRAPPING OR SCARING OF ANIMALS; APPARATUS FOR THE DESTRUCTION OF NOXIOUS ANIMALS OR NOXIOUS PLANTS
- A01M1/00—Stationary means for catching or killing insects
- A01M1/20—Poisoning, narcotising, or burning insects
- A01M1/2022—Poisoning or narcotising insects by vaporising an insecticide
- A01M1/2027—Poisoning or narcotising insects by vaporising an insecticide without heating
- A01M1/2055—Holders or dispensers for solid, gelified or impregnated insecticide, e.g. volatile blocks or impregnated pads
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/08—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing solids as carriers or diluents
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
- A01N65/08—Magnoliopsida [dicotyledons]
Definitions
- the invention features a method of reducing a honey bee parasitic mite infestation in a honey bee hive, the method comprising contacting a hive with the corrugated strip of any of the above- aspects, thereby reducing a bee parasitic mite infestation in the hive.
- the method involves providing 2 corrugated strips/10 frames.
- the corrugated strips are hung from a frame within the hive.
- the invention features a kit for the treatment or prevention of a parasitic mite infestation, the kit comprising the strip of any the above-aspects or any other embodiment of the invention delineated herein.
- the strip is packaged in a moisture resistant material.
- an effective amount of a miticide is meant an amount effective to disrupt a mite biological function.
- honey bee is meant a Hymenopteran insect of the genus Apis.
- honey bee is not limited to the adult form of the insect, but encompasses all honey bee developmental stages, including but not limited to egg, larva, and pupa.
- honey bee parasitic mite any acarid that parasitizes a honey bee or infests a honey bee hive.
- honey bee parasitic mites include Varroa mites and tracheal mites.
- Figure 2 is a graph showing beta acids per bee measured over a 10-day course of treatment with standard HopGuard® or HopGuard II®®.
- Products used to control honey bee parasitic mite infestation reduce, stabilize, or slow the growth of a mite population in a hive or inhibit the growth, survival, reproduction, or other biological function of a honey bee parasitic mite.
- the miticide kills the mite.
- Methods for measuring parasitic mite infestation are known in the art.
- the sampled bees are killed with a wash of alcohol or soapy water and the sample poured through a double strainer.
- a coarse mesh catches the bees but allows the mites to pass through, while a second finer screen catches the mites and allows the liquid to flow away. The mites present in the sample are then counted.
- a miticide of the invention reduces the level of infestation in a hive by at least 10%, 25%, 50%, 75% or even by 100%.
- a miticide of the invention induces at least 50%, 60%, or 70% increase in mite drop relative to an untreated hive.
- the miticide induces 75%, 80%, 90%, or even 95% or 100% increase in mite drop relative to the level prior to treatment. Screening methods are used to identify concentrations of hop derivatives that will be lethal to a mite (e.g., induce at least 70% mite lethality) while minimizing lethal effects on adult bees.
- Miticides of the invention contain concentrations of hop derivatives that have few or no adverse effects on honey bees during any of their life stages, but are effective in killing or disrupting the biological functioning of a mite.
- beta acids a hop derivative
- delivered at 4% concentration killed 87% of exposed mites after four hours while causing 0% lethality in adult bees.
- mites are exposed to varying concentrations of hop derivatives to identify those concentrations that kill 50% to 100% of the exposed mite.
- Adult honey bees are then exposed to concentrations of hop derivatives having miticidal activity to identify those that have a minimal effect on honey bee survival.
- At least 75%, 80%, 85%, 90%, 95%, or 100% of adult bees will survive following exposure to a miticidal composition.
- the effect of hop derivatives on mite and honey bee reproduction is assessed. Screening assays are used to determine the concentration of a miticide that reduces the number of eggs laid by the female mite, reduces the number of eggs that hatch, or reduces the number of mites that grow to reproductive maturity; preferably, the reduction is by at least 25%, 50%, 75%, 85%, 95% or 100%.
- Hop Derivatives are used to determine the concentration of a miticide that reduces the number of eggs laid by the female mite, reduces the number of eggs that hatch, or reduces the number of mites that grow to reproductive maturity; preferably, the reduction is by at least 25%, 50%, 75%, 85%, 95% or 100%.
- a hop derivative is a compound that occurs naturally in a hop plant (Humulus lupulus) or is chemically derived (either through natural biosynthetic procesess (e.g., living organism metabolism (e.g., mammal, plant, bacteria)) or by synthetic processes using human intervention (e.g., chemical synthesis).
- Compositions of the invention include one or more compounds derived from hops.
- hop acids Of particular interest are the hop acids. Hops contain two major organic acid classes, alpha acids and beta acids. Hop acids are the bitter acid components of hops that are used in beer making.
- the compounds of this invention may contain one or more asymmetric centers and thus occur as racemates and racemic mixtures, single enantiomers, individual diastereomers and diastereomeric mixtures. All such isomeric forms of these compounds are expressly included in the present invention.
- the compounds of this invention may also be represented in multiple tautomeric forms, in such instances, the invention expressly includes all tautomeric forms of the compounds described herein. All such isomeric forms of such compounds are expressly included in the present invention. All crystal forms of the compounds described herein are expressly included in the present invention.
- the compounds of this invention, including the compounds of formulae described herein are defined to include derivatives. Derivatives include compounds of the invention that are modified by appending appropriate functionalities to enhance desired properties.
- the amount of active ingredient e.g., hop acid alkali metal salts, hop acid alkaline earth metal salts or combinations thereof
- carrier materials e.g., maltodextrin, cluster dextrin, corn starch, corn syrup solids, glucose, cyclodextrin, arabic gum, calaginan, inuline, partially hydrogenated soybean oil, cellulose, hydroxymethyl cellulose, hydroxyethyl cellulose, hydroxypropyl cellulose, rosin, hypomellose
- carrier materials e.g., maltodextrin, cluster dextrin, corn starch, corn syrup solids, glucose, cyclodextrin, arabic gum, calaginan, inuline, partially hydrogenated soybean oil, cellulose, hydroxymethyl cellulose, hydroxyethyl cellulose, hydroxypropyl cellulose, rosin, hypomellose
- miticides of the invention are formulated as liquids using diluents (e.g., sucrose or glucose solutions, water, juices, other aqueous solutions, water miscible solvents (ethanol, cremophor, dimethylsulf oxide (DMSO), dimethylformamide (DMF), isopropanol (IP A) or glycerol, and other solvents)) to form a solution or slurry.
- diluents e.g., sucrose or glucose solutions, water, juices, other aqueous solutions, water miscible solvents (ethanol, cremophor, dimethylsulf oxide (DMSO), dimethylformamide (DMF), isopropanol (IP A) or glycerol, and other solvents
- a typical miticidal preparation will contain from about 1% to about 95% hop acid, where the bottom of the range is any integer between 5 and 94 and the top of the range is any integer between 6 and 95, where the hop acids are provided in a carrier (e.g., maltodextrin, cluster dextrin, corn starch, corn syrup solids, glucose, cyclodextrin, arabic gum, calaginan, inuline, rosin, partially hydrogenated soybean oil, cellulose, hydroxymethyl cellulose, hydroxyethyl cellulose, hydroxypropyl cellulose, hypomellose) that is suitable for use in methods of producing a product having miticidal activity.
- a carrier e.g., maltodextrin, cluster dextrin, corn starch, corn syrup solids, glucose, cyclodextrin, arabic gum, calaginan, inuline, rosin, partially hydrogenated soybean oil, cellulose, hydroxymethyl cellulose, hydroxyethyl cellulose, hydroxy
- compositions of the invention include at least about 1%, 10%, 20%, 30%, 50%, 60%, 75%, 80%, 90%, or 95% hop acid alkali metal (e.g., sodium, potassium, lithium) or hop acid alkaline earth metal salts (e.g., calcium, magnesium) in a diluent or carrier. Not all of the hop acids need be in the metal form.
- hop acid alkali metal e.g., sodium, potassium, lithium
- hop acid alkaline earth metal salts e.g., calcium, magnesium
- a composition of the invention contains hop acids where 90% are present in the metal form and 10% are present in the acid form; 50% are present in the metal form and 50% in the acid form; and 10% are present in the metal form and 90% in the acid form.
- the preparation includes between 1 and 95% (e.g., 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 25%, 75%, 80%, 90%, 95%) hop acids in a carrier or diluent. Alternatively, such preparations contain from about 20% to about 80% hop acids.
- Compositions containing alpha or beta acids are manufactured by ordinary methods.
- compositions of the invention are also useful for preventing the establishment of an acarid infestation, for treating an established acarid infestation, and for maintaining the health of a hive previously treated for an acarid infestation.
- the composition of the invention is active in the hive for at least forty-one days. This provides for the presence of the miticide for the entirety of the mite life cycle, which typically is completed over the course of twenty-one to thirty days. Where activity is maintained for a shorter period (e.g., seven, fourteen, twenty- one, or thirty days), repeated administration of a composition of the invention may be desired or required. Compositions that are active for longer periods (e.g., two, three, six, nine, or twelve months) are also envisioned. Such compositions may be used for the long-term treatment or prevention of a mite infestation.
- hop beta acids are dispersed in a propylene glycol solvent with polysorbate-60 added as an emulsifier.
- Biodegradable corrugated strips comprising the emulsions are then delivered to the hive.
- the corrugated strips are moistened by contacting them with hop beta acid resins, propylene glycol and polysorbate-60.
- the powdered mixture is delivered to the hive within a semi-permeable pouch that resembles a "teabag".
- the bees rip up the pouch, thereby releasing the powder.
- the powdered hop acids get onto the body of the adult bees and are distributed throughout the hive, thereby killing (or otherwise interfering with mite proliferation or survival) mites present on the bees and inhibiting the mite infestation.
- Alcohols such as glycerin and complex carbohydrates, such as starches may also be used as the "sweetener" ingredient.
- the sweetener is used primarily as an attractant for the insects, however the sweetener also helps to impart a granular structure to the tablets, especially when the sweetener is a sugar. As previously discussed, this granular structure permits the tablet to crumble over time upon the exertion of sufficient forces.
Abstract
Description
Claims
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA2897371A CA2897371C (en) | 2013-01-07 | 2014-01-06 | Compositions and methods for controlling a honey bee parasitic mite infestation |
BR112015016129A BR112015016129A2 (en) | 2013-01-07 | 2014-01-06 | corrugated strip for use in reducing a parasitic mite infestation of the honey bee; corrugated strip prepared by dipping an absorbent strip into a liquid composition; aluminum packaging prepared by dipping a corrugated absorbent strip into a liquid composition; man-made beehive; honey bee product; method of reduction of a parasitic mite infestation of the honey bee in a bee hive; and kit for treating or preventing a parasitic mite infestation |
US14/758,392 US9545110B2 (en) | 2013-01-07 | 2014-01-06 | Compositions and methods for controlling a honey bee parasitic mite infestation |
EP14735165.4A EP2941123A4 (en) | 2013-01-07 | 2014-01-06 | Compositions and methods for controlling a honey bee parasitic mite infestation |
AU2014203897A AU2014203897A1 (en) | 2013-01-07 | 2014-01-06 | Compositions and methods for controlling a honey bee parasitic mite infestation |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361749727P | 2013-01-07 | 2013-01-07 | |
US61/749,727 | 2013-01-07 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2014107664A1 true WO2014107664A1 (en) | 2014-07-10 |
Family
ID=51062494
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2014/010347 WO2014107664A1 (en) | 2013-01-07 | 2014-01-06 | Compositions and methods for controlling a honey bee parasitic mite infestation |
Country Status (6)
Country | Link |
---|---|
US (1) | US9545110B2 (en) |
EP (1) | EP2941123A4 (en) |
AU (1) | AU2014203897A1 (en) |
BR (1) | BR112015016129A2 (en) |
CA (1) | CA2897371C (en) |
WO (1) | WO2014107664A1 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2017042240A1 (en) * | 2015-09-09 | 2017-03-16 | Universität Hohenheim | Lithium metal salt for use in treatment of varroa destructor mite infestation of honey bees |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL244290B (en) * | 2015-11-30 | 2018-11-29 | Keren Ilan | System for prevention of infectious diseases to parent stock |
US20210045383A1 (en) * | 2018-03-12 | 2021-02-18 | Paul Niemczura | Organic metabolite compositions and methods of use as miticides for honey bees |
ES1215109Y (en) * | 2018-03-27 | 2018-09-26 | Chicon Carnero Jose Paulino | Acaricide container strip |
US11213025B1 (en) * | 2018-05-04 | 2022-01-04 | Nathaniel Burns | Device for dispensing pesticides and/or parasiticides to rodents or other animals |
CA3043388A1 (en) | 2018-05-14 | 2019-11-14 | John I. Hass, Inc. | Compositions and methods for controlling a honey bee parasitic mite infestation |
US11622975B2 (en) | 2019-07-16 | 2023-04-11 | The United States Of America, As Represented By The Secretary Of Agriculture | Compositions and methods for improved honey bee health |
DE102020130875A1 (en) | 2020-10-02 | 2022-04-07 | Interbran Nature Gmbh | Release system to combat parasites |
WO2023137555A1 (en) * | 2022-01-21 | 2023-07-27 | Nature Recombined Sciences Inc. | Aqueous hop extracts and their use as antimicrobial agents |
Citations (46)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB592090A (en) * | 1943-11-26 | 1947-09-08 | Jose Rovira Cases | An improved honeycomb for a beehive |
US4299816A (en) | 1977-05-03 | 1981-11-10 | Polyakov Anisim A | Acaricidal preparation for diagnosis and control of ectoparasites of bees |
US4682380A (en) | 1985-01-14 | 1987-07-28 | Alain Martin | Box for beekeeping for the creation of a bee colony, change of queen from a hive in activity and partial restriction of brood rearing |
US4775534A (en) | 1986-02-05 | 1988-10-04 | Fermone Chemicals, Inc. | Miticidal composition and method for controlling spider mite populations |
US4837216A (en) | 1987-02-03 | 1989-06-06 | Bayer Aktiengesellschaft | Agents against protozoa in insects |
US4867731A (en) | 1988-03-15 | 1989-09-19 | Joel Willard | Detection of infestation of bees |
US4876265A (en) | 1983-04-14 | 1989-10-24 | Ciba-Geigy Corporation | Process and compositions for controlling mites parasitizing on honey bees |
US5023359A (en) | 1989-07-03 | 1991-06-11 | Benechim, S.A. | Use of organic salts of copper for the treatment of honeybee's parasitic diseases |
US5069651A (en) | 1990-07-23 | 1991-12-03 | Arndt Maurice W | Method and apparatus for removing parasites from bees |
US5070091A (en) | 1989-01-09 | 1991-12-03 | Bayer Aktiengesellschaft | Substituted 1,2,4-triazinediones useful against protozoa in insects |
US5135758A (en) | 1988-11-03 | 1992-08-04 | Institute National De La Recherche Agronomique (Inra) | Process for combatting "varroatosis" by biological means and devices for implementing this process |
US5227162A (en) | 1989-05-19 | 1993-07-13 | Officine Ferrari S.N.C. Di Carlo E Mario Ferrari & Co. | Acaricidal composition and use thereof in disinfesting treatments |
US5230894A (en) | 1991-02-11 | 1993-07-27 | Robert Jean Edouard | Acaricidal composition suitable for use against varroatosis in bees and device containing same |
US5312622A (en) | 1989-06-27 | 1994-05-17 | Richter Gedeon Vegyeszeti Gyar Rt. | Acaricidal compositions and process for preparing same |
US5348511A (en) | 1993-05-12 | 1994-09-20 | The United States Of America As Represented By The Secretary Of Agriculture | Beehive-mounted device for utilizing honeybees (hymenoptera: apidae) in the dissemination of biocontrol agents |
EP0816430A2 (en) | 1996-06-28 | 1998-01-07 | Research Association For Biotechnology Of Agricultural Chemicals | Biodegradable sustained-release preparation, biodegradable pheromone dispenser and biodegradable pest controlling agent |
US5750129A (en) | 1992-08-28 | 1998-05-12 | Phero Tech Inc. | Composite polymer matrices for controlled release of semiochemicals |
US5849317A (en) | 1992-09-04 | 1998-12-15 | Regents Of The University Of California | Methods and compositions for repelling ants, wasps, and termites with repellents |
US6010390A (en) | 1998-06-08 | 2000-01-04 | Harper; William A. | Crop pollination method by insects |
US6037374A (en) | 1997-11-19 | 2000-03-14 | The United States Of America As Represented By The Secretary Of Agriculture | Composition and method for the control of parasitic mites in honey bees |
US6096350A (en) | 1995-09-08 | 2000-08-01 | Alcide Corporation | Compositions and methods for prevention and treatment of diseases associated with honey bees |
US6204283B1 (en) | 1998-07-14 | 2001-03-20 | American Cyanamid Company | Parasitic mite control on beneficial insects |
US6221375B1 (en) | 1996-03-12 | 2001-04-24 | University Of Southampton | Pesticidal or herbicidal compositions |
US20010014346A1 (en) | 1996-06-12 | 2001-08-16 | Max Watkins | Organic compounds |
US6277371B1 (en) | 1999-05-20 | 2001-08-21 | Oldrich Haragsim | Biological control of Varroa mites in honeybee hives with Hirsutella thompsonii |
US20020094756A1 (en) | 2001-01-17 | 2002-07-18 | Labesque Serge J. | Pest-trapping tray for beehive |
US20020151249A1 (en) | 2001-04-12 | 2002-10-17 | Scheuneman Theodore W. | Evaporator for the treatment of honey bee diseases and undesirable hive conditions |
US6468129B1 (en) | 2000-03-03 | 2002-10-22 | Granville Griffith | Beehive bottom board for reducing parasite infestation |
US6475061B1 (en) | 2000-11-01 | 2002-11-05 | Board Of Trustees Of Michigan State University | Method and apparatus for control of mites in a beehive |
US20020182977A1 (en) | 2001-02-02 | 2002-12-05 | The Regents Of The University Of California | Synthetic bee pollen foraging pheromone and uses thereof |
US20030027490A1 (en) | 2001-08-06 | 2003-02-06 | Wilkinson Thomas Wilson | Beatrice beehive |
US20030044443A1 (en) | 2001-02-28 | 2003-03-06 | Erickson Eric H. | Control of parasitic mites of honey bees |
US6585557B1 (en) | 1998-12-23 | 2003-07-01 | Universiteit Gent | Beeswax mimetic substances and methods of operating beehives |
US20030190860A1 (en) | 2002-04-04 | 2003-10-09 | Vanderpool Harry E. | Separating parasites from bees |
US20040077291A1 (en) | 2000-09-19 | 2004-04-22 | Bayer Pharmaceuticals Corporation | Antiparasite entrance gate for honey-bee populations |
US20040229542A1 (en) | 2000-10-13 | 2004-11-18 | Vaclav Ruzicka | Treatment fluid dispenser for control of mites |
US6820773B1 (en) | 2002-12-31 | 2004-11-23 | Apis Discoveries, L.L.C. | Delivery system for volatile compounds |
US20050048093A1 (en) | 2001-11-23 | 2005-03-03 | Norberto Milani | Methods and reagents for the control of infestations of parasites |
US20050095954A1 (en) | 2003-11-04 | 2005-05-05 | Jose Castillo | Method of controlling pests |
US20060009122A1 (en) | 2004-07-12 | 2006-01-12 | Swanson Melvin J | Methods and reagents for treating honeybees for parasitic mites |
US20060008492A1 (en) | 2004-07-09 | 2006-01-12 | Pablo Janowicz | Composition and method for delivering chemical agent to insects |
US20060141904A1 (en) | 2004-12-29 | 2006-06-29 | Teal Peter E A | In-hive trap and attractant composition for the control of the small hive beetle, Aethina tumida |
US20070026765A1 (en) | 2005-08-01 | 2007-02-01 | Renn Richard M | Composition and method for the control of parasitic mites of honey bees |
US20070059333A1 (en) | 2005-09-15 | 2007-03-15 | Volby Stuart A | Pesticide strips for control of mites in honeybees |
US20080026673A1 (en) * | 2006-03-31 | 2008-01-31 | Gene Probasco | Compositions and methods for controlling a honey bee parasitic mite |
WO2012170420A2 (en) | 2011-06-06 | 2012-12-13 | John I. Haas, Inc. | Compositions and methods for controlling a honey bee parasitic mite infestation |
Family Cites Families (60)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1058975A (en) | 1962-08-15 | 1967-02-15 | Steiner Inc S S | Method of treating hops |
US3615660A (en) | 1969-06-11 | 1971-10-26 | Pfizer | Hop extract emulsion and preparation and use thereof |
CH514988A (en) | 1969-08-11 | 1971-11-15 | Ciba Geigy Ag | Pesticides |
US4002683A (en) | 1971-05-03 | 1977-01-11 | Kalsec, Inc. | Process for isomerizing alpha acids to iso-alpha acids |
JPS5024244Y2 (en) | 1971-06-24 | 1975-07-22 | ||
US4148873A (en) | 1976-11-05 | 1979-04-10 | S. S. Steiner, Inc. | Method for treating the skin with extracts of hops |
US4170638A (en) | 1976-11-05 | 1979-10-09 | S. S. Steiner, Inc. | Method for producing a deodorant |
US4281061A (en) | 1979-07-27 | 1981-07-28 | Syva Company | Double antibody for enhanced sensitivity in immunoassay |
JPS5780304U (en) | 1980-11-06 | 1982-05-18 | ||
US4562794A (en) | 1984-01-30 | 1986-01-07 | Bend Research, Inc. | Pest control in animals |
US4844939A (en) | 1984-02-28 | 1989-07-04 | Kalamazoo Holdings, Inc. | Separation of the constitutents of CO2 hop extracts |
EP0339147B1 (en) | 1988-04-27 | 1994-03-02 | Miller Brewing Company | Anactinic hopping materials and method of preparation |
EP0212623A3 (en) | 1985-08-30 | 1987-12-16 | Hopstabil Hopfenverarbeitungs-Gesellschaft mbH | Flavouring additive for foods and beverages |
DE3538688A1 (en) * | 1985-10-31 | 1987-05-07 | Bayer Ag | METHOD FOR COMBATING PARASITOSIS IN BEES |
US4847292A (en) | 1987-04-03 | 1989-07-11 | International Flavors & Fragrances Inc. | Repelling animals with compositions comprising citronellyl nitrile, citronellol, alpha-terpinyl methyl ether and lemon oil |
FR2628297B1 (en) | 1988-03-09 | 1991-09-13 | Univ Gent | AQUACULTURE FOOD |
US5166449A (en) | 1988-08-15 | 1992-11-24 | Kalamazoo Holdings, Inc. | Synthesis of hexahydrolupulone, novel forms thereof, and its use as a selective inhibitor of cell growth and multiplication |
US5082975A (en) | 1988-08-15 | 1992-01-21 | Kalamazoo Holdings, Inc. | Synthesis of hexahydrolupulone, novel forms thereof, and its use as a selective inhibitor of cell growth and multiplication |
GB9002505D0 (en) | 1990-02-05 | 1990-04-04 | Sandoz Ltd | Improvements in or relating to mechanical devices |
US5372817A (en) | 1991-01-03 | 1994-12-13 | W. R. Grace & Co.-Conn. | Insecticidal compositions derived from neem oil and neem wax fractions |
US5286506A (en) | 1992-10-29 | 1994-02-15 | Bio-Technical Resources | Inhibition of food pathogens by hop acids |
US5370863A (en) | 1992-12-16 | 1994-12-06 | Miller Brewing Company | Oral care compositions containing hop acids and method |
AT404469B (en) | 1994-05-06 | 1998-11-25 | Tulln Zuckerforschung Gmbh | METHOD FOR THE PRESERVATION OF SUGAR-BASED PLANT EXTRACTS OR. JUICES |
US5583262A (en) | 1994-11-10 | 1996-12-10 | Maye; John P. | Solid salts of hop acids |
US5827895A (en) | 1996-02-27 | 1998-10-27 | Regents Of The University Of Minnesota | Hexahydrolupulones useful as anticancer agents |
AU2212397A (en) | 1996-03-15 | 1997-10-01 | Kalamazoo Holdings, Inc. | Solid hop acid salt compositions |
US6083254A (en) | 1996-03-22 | 2000-07-04 | Evans; Randy Allan | Reusable hot/cold therapeutic compress appliance |
AT406156B (en) | 1996-08-13 | 2000-03-27 | Tulln Zuckerforschung Gmbh | ADDITIVES FOR SPRAY CONCRETE |
WO1999009842A1 (en) | 1997-08-22 | 1999-03-04 | Nippon Shinyaku Co., Ltd. | Food-preservative composition |
US6251461B1 (en) | 1997-10-10 | 2001-06-26 | S. S. Steiner, Inc. | Antimicrobial activity of hops extract against Clostridium botulinum, Clostridium difficile and Helicobacter pylori |
GB9825839D0 (en) * | 1998-11-26 | 1999-01-20 | Univ Cardiff | Foulbrood treatments |
US6451365B1 (en) | 2000-07-14 | 2002-09-17 | Rhodia Inc. | Antibacterial composition for control of gram positive bacteria in food applications |
US6476015B1 (en) | 1999-07-22 | 2002-11-05 | University Of South Florida | N-thiolated β-lactam antibiotics |
US6475537B1 (en) * | 2000-07-27 | 2002-11-05 | Rhodia Inc. | Hops acid antibacterial compositions |
MXPA02000878A (en) | 1999-07-27 | 2002-10-23 | Rhodia | Hops acid antibacterial compositions. |
EA200200947A1 (en) | 2000-03-07 | 2003-02-27 | Янссен Фармацевтика Н.В. | PESTICIDAL COMPOSITIONS AND THEIR APPLICATION AS A MEANS OF PROTECTION |
US20020051804A1 (en) | 2000-05-18 | 2002-05-02 | Gene Probasco | Pesticides made from hop extracts |
US8293258B2 (en) | 2000-05-18 | 2012-10-23 | John I. Hass, Inc. | Pesticide treatments made from hop extracts |
US8153146B2 (en) | 2000-05-18 | 2012-04-10 | John I. Haas | Pesticide and fungicide treatments made from hop extracts |
US20030060379A1 (en) | 2000-05-26 | 2003-03-27 | The Procter & Gamble Company | Pesticides |
US6450858B1 (en) * | 2001-02-19 | 2002-09-17 | Edmund P. Schmitz | Beehive movable top entrance |
EP1363510B1 (en) | 2001-03-02 | 2007-05-16 | Kalsec, Incorporated | Labiatae herb extracts and hop extracts for extending the color life and inhibiting the growth of microorganisms in fresh meat, fish and poultry |
US20030010817A1 (en) * | 2001-07-06 | 2003-01-16 | Lingle John E. | Method of forming a thermoformed corrugated container and a corrugated container formed thereby |
US6766613B2 (en) | 2001-11-16 | 2004-07-27 | University Of Florida Research Foundation, Inc. | Materials and methods for controlling pests |
US20060013870A1 (en) | 2002-05-06 | 2006-01-19 | Kuhrts Eric H | Pharmaceutical compositions of hops resins |
NZ536090A (en) | 2002-05-17 | 2007-06-29 | Steiner Inc S S | Improved application for hop acids as anti-microbial agents |
US20030228814A1 (en) * | 2002-06-07 | 2003-12-11 | Barney Michael C. | Antibacterial packaging material including hop acids |
ES2221550B1 (en) | 2003-02-10 | 2006-01-01 | Viscofan Sa | ANTIMICROBIAL WRAPPING. |
US20040175480A1 (en) | 2003-03-03 | 2004-09-09 | Kraft Foods Holdings, Inc. | Hop beta acid compositions for use in food products |
WO2005022167A2 (en) | 2003-08-29 | 2005-03-10 | The University Of North Carolina At Greensboro | Compounds that act to modulate insect growth and methods and systems for identifying such compounds |
US7087849B2 (en) | 2004-04-20 | 2006-08-08 | One Pass Farm Equipment, Llc | Switch device and method for controlling a sprayer |
JP4318595B2 (en) | 2004-06-16 | 2009-08-26 | 富士通株式会社 | Mobile terminal |
US8071136B2 (en) | 2006-04-21 | 2011-12-06 | Bioactives, Inc. | Water-soluble pharmaceutical compositions of hops resins |
US20090104288A1 (en) | 2006-11-15 | 2009-04-23 | John I. Haas, Inc. | Compositions and methods for inhibiting a honey bee pathogen infection or controlling a hive infestation |
WO2009098300A2 (en) | 2008-02-08 | 2009-08-13 | Basf Se | The use of hops-derivatives for controlling parasites in and on animals |
CA2717730A1 (en) | 2008-02-08 | 2009-08-13 | Haas, John I. | Compositions and methods for arachnid control |
WO2010088645A2 (en) * | 2009-02-02 | 2010-08-05 | Ecoblend, Llc | Pesticidal compositions and methods of use thereof |
HUP0900306A2 (en) | 2009-05-15 | 2010-11-29 | Bartheldne Abri Judit Von | Composition for exterminating acarus pests of bees, and process for exterminating acarus pests of bees |
US20130145679A1 (en) * | 2011-12-12 | 2013-06-13 | John Henry Nenninger | Pheromone Glue Beetle Trap |
US9295252B2 (en) * | 2012-06-07 | 2016-03-29 | John I. Haas, Inc. | Compositions and methods for controlling a tropilaelaps parasitic mite |
-
2014
- 2014-01-06 CA CA2897371A patent/CA2897371C/en active Active
- 2014-01-06 BR BR112015016129A patent/BR112015016129A2/en not_active IP Right Cessation
- 2014-01-06 US US14/758,392 patent/US9545110B2/en active Active
- 2014-01-06 EP EP14735165.4A patent/EP2941123A4/en not_active Withdrawn
- 2014-01-06 WO PCT/US2014/010347 patent/WO2014107664A1/en active Application Filing
- 2014-01-06 AU AU2014203897A patent/AU2014203897A1/en not_active Abandoned
Patent Citations (55)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB592090A (en) * | 1943-11-26 | 1947-09-08 | Jose Rovira Cases | An improved honeycomb for a beehive |
US4299816A (en) | 1977-05-03 | 1981-11-10 | Polyakov Anisim A | Acaricidal preparation for diagnosis and control of ectoparasites of bees |
US4876265A (en) | 1983-04-14 | 1989-10-24 | Ciba-Geigy Corporation | Process and compositions for controlling mites parasitizing on honey bees |
US4682380A (en) | 1985-01-14 | 1987-07-28 | Alain Martin | Box for beekeeping for the creation of a bee colony, change of queen from a hive in activity and partial restriction of brood rearing |
US4775534A (en) | 1986-02-05 | 1988-10-04 | Fermone Chemicals, Inc. | Miticidal composition and method for controlling spider mite populations |
US4837216A (en) | 1987-02-03 | 1989-06-06 | Bayer Aktiengesellschaft | Agents against protozoa in insects |
US4867731A (en) | 1988-03-15 | 1989-09-19 | Joel Willard | Detection of infestation of bees |
US5135758A (en) | 1988-11-03 | 1992-08-04 | Institute National De La Recherche Agronomique (Inra) | Process for combatting "varroatosis" by biological means and devices for implementing this process |
US5070091A (en) | 1989-01-09 | 1991-12-03 | Bayer Aktiengesellschaft | Substituted 1,2,4-triazinediones useful against protozoa in insects |
US5227162A (en) | 1989-05-19 | 1993-07-13 | Officine Ferrari S.N.C. Di Carlo E Mario Ferrari & Co. | Acaricidal composition and use thereof in disinfesting treatments |
US5312622A (en) | 1989-06-27 | 1994-05-17 | Richter Gedeon Vegyeszeti Gyar Rt. | Acaricidal compositions and process for preparing same |
US5023359A (en) | 1989-07-03 | 1991-06-11 | Benechim, S.A. | Use of organic salts of copper for the treatment of honeybee's parasitic diseases |
US5069651A (en) | 1990-07-23 | 1991-12-03 | Arndt Maurice W | Method and apparatus for removing parasites from bees |
US5230894A (en) | 1991-02-11 | 1993-07-27 | Robert Jean Edouard | Acaricidal composition suitable for use against varroatosis in bees and device containing same |
US5750129A (en) | 1992-08-28 | 1998-05-12 | Phero Tech Inc. | Composite polymer matrices for controlled release of semiochemicals |
US5849317A (en) | 1992-09-04 | 1998-12-15 | Regents Of The University Of California | Methods and compositions for repelling ants, wasps, and termites with repellents |
US5348511A (en) | 1993-05-12 | 1994-09-20 | The United States Of America As Represented By The Secretary Of Agriculture | Beehive-mounted device for utilizing honeybees (hymenoptera: apidae) in the dissemination of biocontrol agents |
US6096350A (en) | 1995-09-08 | 2000-08-01 | Alcide Corporation | Compositions and methods for prevention and treatment of diseases associated with honey bees |
US6221375B1 (en) | 1996-03-12 | 2001-04-24 | University Of Southampton | Pesticidal or herbicidal compositions |
US20010014346A1 (en) | 1996-06-12 | 2001-08-16 | Max Watkins | Organic compounds |
US6646014B2 (en) | 1996-06-13 | 2003-11-11 | Vita (Europe) Limited | Organic compounds |
EP0816430A2 (en) | 1996-06-28 | 1998-01-07 | Research Association For Biotechnology Of Agricultural Chemicals | Biodegradable sustained-release preparation, biodegradable pheromone dispenser and biodegradable pest controlling agent |
US6037374A (en) | 1997-11-19 | 2000-03-14 | The United States Of America As Represented By The Secretary Of Agriculture | Composition and method for the control of parasitic mites in honey bees |
US6010390A (en) | 1998-06-08 | 2000-01-04 | Harper; William A. | Crop pollination method by insects |
US6204283B1 (en) | 1998-07-14 | 2001-03-20 | American Cyanamid Company | Parasitic mite control on beneficial insects |
US6585557B1 (en) | 1998-12-23 | 2003-07-01 | Universiteit Gent | Beeswax mimetic substances and methods of operating beehives |
US6277371B1 (en) | 1999-05-20 | 2001-08-21 | Oldrich Haragsim | Biological control of Varroa mites in honeybee hives with Hirsutella thompsonii |
US6468129B1 (en) | 2000-03-03 | 2002-10-22 | Granville Griffith | Beehive bottom board for reducing parasite infestation |
US20040077291A1 (en) | 2000-09-19 | 2004-04-22 | Bayer Pharmaceuticals Corporation | Antiparasite entrance gate for honey-bee populations |
US20040229542A1 (en) | 2000-10-13 | 2004-11-18 | Vaclav Ruzicka | Treatment fluid dispenser for control of mites |
US6837770B2 (en) | 2000-10-13 | 2005-01-04 | Vaclav Ruzicka | Treatment fluid dispenser for control of mites |
US6475061B1 (en) | 2000-11-01 | 2002-11-05 | Board Of Trustees Of Michigan State University | Method and apparatus for control of mites in a beehive |
US20020094756A1 (en) | 2001-01-17 | 2002-07-18 | Labesque Serge J. | Pest-trapping tray for beehive |
US20020182977A1 (en) | 2001-02-02 | 2002-12-05 | The Regents Of The University Of California | Synthetic bee pollen foraging pheromone and uses thereof |
US6595828B2 (en) | 2001-02-02 | 2003-07-22 | The Regents Of The University Of California | Synthetic bee pollen foraging pheromone and uses thereof |
US6843985B2 (en) | 2001-02-28 | 2005-01-18 | The United States Of America As Represented By The Secretary Of Agriculture | Control of parasitic mites of honey bees |
US20050090560A1 (en) | 2001-02-28 | 2005-04-28 | The United States Of America, As Represented By The Secretary Of Agriculture | Control of parasitic mites of honey bees |
US20030044443A1 (en) | 2001-02-28 | 2003-03-06 | Erickson Eric H. | Control of parasitic mites of honey bees |
US20020151249A1 (en) | 2001-04-12 | 2002-10-17 | Scheuneman Theodore W. | Evaporator for the treatment of honey bee diseases and undesirable hive conditions |
US6620025B2 (en) | 2001-04-12 | 2003-09-16 | Theodore W. Scheuneman | Evaporator for the treatment of honey bee diseases and undesirable hive conditions |
US20030027490A1 (en) | 2001-08-06 | 2003-02-06 | Wilkinson Thomas Wilson | Beatrice beehive |
US20050048093A1 (en) | 2001-11-23 | 2005-03-03 | Norberto Milani | Methods and reagents for the control of infestations of parasites |
US6702645B2 (en) | 2002-04-04 | 2004-03-09 | Harry E. Vanderpool | Separating parasites from bees |
US20030190860A1 (en) | 2002-04-04 | 2003-10-09 | Vanderpool Harry E. | Separating parasites from bees |
US6820773B1 (en) | 2002-12-31 | 2004-11-23 | Apis Discoveries, L.L.C. | Delivery system for volatile compounds |
US20050095954A1 (en) | 2003-11-04 | 2005-05-05 | Jose Castillo | Method of controlling pests |
US20060008492A1 (en) | 2004-07-09 | 2006-01-12 | Pablo Janowicz | Composition and method for delivering chemical agent to insects |
US20060009122A1 (en) | 2004-07-12 | 2006-01-12 | Swanson Melvin J | Methods and reagents for treating honeybees for parasitic mites |
US7137864B2 (en) | 2004-07-12 | 2006-11-21 | Swanson Melvin J | Methods and reagents for treating honeybees for parasitic mites |
US20060141904A1 (en) | 2004-12-29 | 2006-06-29 | Teal Peter E A | In-hive trap and attractant composition for the control of the small hive beetle, Aethina tumida |
US20070026765A1 (en) | 2005-08-01 | 2007-02-01 | Renn Richard M | Composition and method for the control of parasitic mites of honey bees |
US20070059333A1 (en) | 2005-09-15 | 2007-03-15 | Volby Stuart A | Pesticide strips for control of mites in honeybees |
WO2007037905A2 (en) * | 2005-09-15 | 2007-04-05 | Mann Lake, Ltd. | Pesticide strips for control of mites in honeybees |
US20080026673A1 (en) * | 2006-03-31 | 2008-01-31 | Gene Probasco | Compositions and methods for controlling a honey bee parasitic mite |
WO2012170420A2 (en) | 2011-06-06 | 2012-12-13 | John I. Haas, Inc. | Compositions and methods for controlling a honey bee parasitic mite infestation |
Non-Patent Citations (9)
Title |
---|
"Encyclopedia of Reagents for Organic Synthesis", 1995, JOHN WILEY AND SONS |
ANR-1186 SMALL HIVE BEETLE LIFE CYCLE WHAT THE LOOK LIKE EGGS TO ADULTS IN 45 DAYS, 1 March 2001 (2001-03-01) |
HELENA NORDENFORS ET AL.: "Effects of Temperature and Humidity on Oviposition, Molting and Longevity of Dermanyssus gallinae (Acri Dermanyssidae", JOURNAL OF MEDICAL ENTOMOLOGY, 1 January 1999 (1999-01-01), pages 66 - 68 |
L. FIESER; M. FIESER: "Fieser and Fieser's Reagents for Organic Synthesis", 1994, JOHN WILEY AND SONS |
M. VERZELE; D. DE KEUKELEIRE: "Chemistry and Analysis of Hop and Beer Bitter Acids", 1991, ELSEVIER |
R. LAROCK: "Comprehensive Organic Transformations", 1989, VCH PUBLISHERS |
RIETH ET AL., JOURNAL OF APICULTURE RESEARCH, vol. 25, no. 2, 1986, pages 78 - 84 |
See also references of EP2941123A4 |
T. W. GREENE; P. G. M. WUTS: "Protective Groups in Organic Synthesis", 1991, JOHN WILEY AND SONS |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2017042240A1 (en) * | 2015-09-09 | 2017-03-16 | Universität Hohenheim | Lithium metal salt for use in treatment of varroa destructor mite infestation of honey bees |
US10375963B2 (en) | 2015-09-09 | 2019-08-13 | Universität Hohenheim | Alkali metal salt for use in treatment of Varroa destructor mite infestation of honey bees |
US10980238B2 (en) | 2015-09-09 | 2021-04-20 | Universität Hohenheim | Alkali metal salt for use in treatment of varroa destructor mite infestation of honey bees |
US11723366B2 (en) | 2015-09-09 | 2023-08-15 | Universität Hohenheim | Alkali metal salt for use in treatment of Varroa destructor mite infestation of honey bees |
Also Published As
Publication number | Publication date |
---|---|
EP2941123A4 (en) | 2016-06-01 |
BR112015016129A2 (en) | 2017-07-11 |
CA2897371A1 (en) | 2014-07-10 |
US20150366215A1 (en) | 2015-12-24 |
AU2014203897A1 (en) | 2015-07-23 |
CA2897371C (en) | 2022-08-30 |
US9545110B2 (en) | 2017-01-17 |
EP2941123A1 (en) | 2015-11-11 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US7597912B2 (en) | Compositions and methods for controlling a honey bee parasitic mite | |
US9545110B2 (en) | Compositions and methods for controlling a honey bee parasitic mite infestation | |
US20140127968A1 (en) | Methods and compositions for controlling a honey bee parasitic mite infestation | |
US9295252B2 (en) | Compositions and methods for controlling a tropilaelaps parasitic mite | |
US20090104288A1 (en) | Compositions and methods for inhibiting a honey bee pathogen infection or controlling a hive infestation | |
EP2249652A1 (en) | Compositions and methods for arachnid control | |
NZ619404B2 (en) | Compositions and methods for controlling a honey bee parasitic mite infestation | |
AU2013205676A1 (en) | Compositions and methods for controlling a honey bee parasitic mite |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
121 | Ep: the epo has been informed by wipo that ep was designated in this application |
Ref document number: 14735165 Country of ref document: EP Kind code of ref document: A1 |
|
WWE | Wipo information: entry into national phase |
Ref document number: 14758392 Country of ref document: US |
|
WWE | Wipo information: entry into national phase |
Ref document number: 2014735165 Country of ref document: EP |
|
ENP | Entry into the national phase |
Ref document number: 2897371 Country of ref document: CA |
|
NENP | Non-entry into the national phase |
Ref country code: DE |
|
REG | Reference to national code |
Ref country code: BR Ref legal event code: B01A Ref document number: 112015016129 Country of ref document: BR |
|
ENP | Entry into the national phase |
Ref document number: 2014203897 Country of ref document: AU Date of ref document: 20140106 Kind code of ref document: A |
|
ENP | Entry into the national phase |
Ref document number: 112015016129 Country of ref document: BR Kind code of ref document: A2 Effective date: 20150703 |